'Nativitate', which is sadly wasted on what amounts to a single room before the Bonus Boss.

A new alt boss theme, 'Cerebrum Dispersio', which apparently randomly replaces the standard boss music.

Definitely gets the player pumped throughout the chaotic battle that is ULTRA GREED, Greed Mode's Final Boss.

A variation/ Boss Remix on the title theme, 'Chorus Mortus'.

The Forgotten, the Secret Room theme, is a calm theme compared to the rest of the game.

Thankfully Repentance added it back and added a new version once you achieve Dead God.

Hush (Jesus Loves Uke), the creepy song that is supposed to replace 'Jesus Loves Me' but was cut due to ESRB rating concerns.

Like 'Hericide', the in-game version of 'Fallen Angel' is a bit different, with heavier emphasis on the vocals, making it even creepier.

The Dark Room's Final Boss gets the incredibly creepy 'The Fallen Angel'.

The Chest's Final Boss receives 'Ascension'.

The Chest receives a theme worthy of The Very Definitely Final Dungeon: 'Sketches of Pain'.

While Sheol gets the disturbingly demonic 'Duress'.The Cathedral itself gets a nice, calming theme in the form of 'Everlasting Hymn'.There's an equally epic vocal track for Isaac's own boss fight: 'Infanticide'.The in-game version of 'Hericide' is a bit different with a heavier emphasis on the drums, which makes it even more awesome. Satan (and Mega Satan) gets one of the most amazingly epic vocal tracks for his new battle theme: 'Hericide'.The theme of Mom's Heart/It Lives, 'Ventricide', which periodically switches between intense and creepy in a heartbeat.Mom gets the fast-paced and frantic 'Matricide' as her new battle theme, adding a strong sense of panic and urgency to the fight.While The Cellar has always been That One Level, 'Periculum', the driving rock theme that plays as you battle through it, more than makes up for it.'Crusade' is a rocking boss theme that prepares you for the various fights of this game.And it's creepy as hell! Made worse by the fact that it's called ' Jesus Loves Me '. It comes as a great surprise because it replaces the BGM that usually plays on that sequence. The tune that plays on the credits after defeating It Lives! for the first time.It certainly shows that Sheol is cold, bleak, and empty.

yet some parts are oddly soothing, to a point. The music that plays in Sheol, 'A Mourner Unto Sheol', is incredibly eerie and foreboding, to the point where it's arguably creepier than Rebirth's version.Sheol's boss, on the other hand, has 'Enmity of the Dark Lord', which also does a fantastic job getting the player pumped up for the fight.The theme of Mom's Heart and It Lives, '.Be Done'.The theme for fighting Mom, 'Thine Wrath.', especially the parts where the chorus joins in showing that Isaac has a little hope.The normal boss theme, Divine Combat and the alternate theme, 'Crusade', both set a hectic feel for the first few boss battles.It helps that it's the Background Music for the first level, so it's going to worm its way into your ears at one point or another. 'Sacrificial', the Basement's theme, sets up the haunting atmosphere of the game quite nicely.Completely captures the sinister, yet bright tone of the game. The main theme (and arguably, Isaac's theme) of the game, 'The Binding of Isaac'.

Cerebrum dispersio by ridiculon